
In the Outlook Desktop App, you can use multiple email signatures within the same account. (Want to use an HTML signature, then read this article) You can set different signatures for new messages and replies. Create or paste your signature in the text area. If you have multiple email accounts, you will need to select the account that you want to use for the signature.

Create or Paste your Signature in the Edit Signature text area.You can create a separate signature for your reply emails for example. Make sure you use a recognizable name so you can easily select the correct signature in your emails later.

Click on Signatures in the toolbar and select Signatures… from the dropdown menu
